Thirumala-Devi Kanneganti Selected Research

Inflammasomes

11/2022	Bacillus anthracis induces NLRP3 inflammasome activation and caspase-8-mediated apoptosis of macrophages to promote lethal anthrax.
1/2022	The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice.
12/2021	Caspase-6 promotes activation of the caspase-11-NLRP3 inflammasome during gram-negative bacterial infections.
10/2021	NLRP3 inflammasome activation triggers gasdermin D-independent inflammation.
1/2021	Advances in Understanding Activation and Function of the NLRC4 Inflammasome.
1/2021	NLRP3 inflammasome in cancer and metabolic diseases.
1/2021	DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response.
1/2021	AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence.
1/2021	Role of inflammasomes/pyroptosis and PANoptosis during fungal infection.
12/2020	ZBP1 promotes fungi-induced inflammasome activation and pyroptosis, apoptosis, and necroptosis (PANoptosis).

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Thirumala-Devi Kanneganti Research Topics

Disease

70	Infections 11/2022 - 11/2006
62	Inflammation (Inflammations) 02/2022 - 08/2007
26	Neoplasms (Cancer) 11/2022 - 01/2010
14	Carcinogenesis 02/2022 - 10/2010
12	Virus Diseases (Viral Diseases) 11/2022 - 12/2006
10	Colitis 12/2020 - 03/2010
8	Melanoma (Melanoma, Malignant) 10/2021 - 05/2015
7	Autoimmune Diseases (Autoimmune Disease) 12/2020 - 02/2011
7	Necrosis 10/2017 - 03/2006
6	Colorectal Neoplasms (Colorectal Cancer) 02/2022 - 10/2010
6	Sepsis (Septicemia) 01/2021 - 10/2010
6	Bites and Stings (Sting) 01/2020 - 11/2014
6	Fever (Fevers) 01/2020 - 02/2011
5	COVID-19 01/2022 - 11/2020
5	Obesity 01/2021 - 07/2011
5	Osteomyelitis 01/2020 - 01/2014
5	Skin Diseases (Skin Disease) 11/2019 - 01/2014
5	Bacterial Infections (Bacterial Infection) 01/2018 - 06/2007
4	Mycoses (Diseases, Fungus) 01/2022 - 07/2009
4	Communicable Diseases (Infectious Diseases) 12/2021 - 01/2017
4	Atherosclerosis 01/2021 - 07/2011
4	Familial Mediterranean Fever (Periodic Disease) 11/2020 - 02/2017
4	Chronic recurrent multifocal osteomyelitis 01/2020 - 01/2014
4	Multiple Sclerosis 01/2019 - 05/2010
4	Bone Diseases (Bone Disease) 04/2016 - 01/2014
4	Lyme Disease (Disease, Lyme) 01/2016 - 06/2010
3	Anthrax 11/2022 - 08/2007
3	Cytokine Release Syndrome 01/2022 - 11/2020
3	Coronavirus Infections 01/2022 - 10/2020
3	Metabolic Diseases (Metabolic Disease) 01/2021 - 03/2015
3	Shock 01/2021 - 10/2010
3	Human Influenza (Influenza) 12/2020 - 01/2018
3	Rheumatoid Arthritis 01/2020 - 01/2014
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2019 - 01/2015
3	Arthritis (Polyarthritis) 02/2016 - 04/2010
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 04/2012 - 05/2010
2	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2022 - 05/2015
2	Pseudomonas Infections 01/2022 - 01/2018
2	Leukemia 01/2021 - 06/2015
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2021 - 11/2020
2	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2020 - 01/2017
2	Breast Neoplasms (Breast Cancer) 12/2019 - 01/2017
2	Neoplasm Metastasis (Metastasis) 01/2019 - 01/2017
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019 - 02/2016
2	Atopic Dermatitis (Atopic Eczema) 01/2019 - 04/2015

Drug/Important Bio-Agent (IBA)

109	InflammasomesIBA 11/2022 - 12/2006
39	CytokinesIBA 10/2022 - 12/2008
21	Proteins (Proteins, Gene)FDA Link 11/2022 - 08/2006
18	Interleukin-18 (Interleukin 18)IBA 12/2020 - 12/2006
15	NLR ProteinsIBA 01/2018 - 06/2007
10	Phosphotransferases (Kinase)IBA 11/2022 - 01/2012
10	Caspase 8 (Caspase-8)IBA 11/2021 - 01/2015
10	NucleotidesIBA 01/2021 - 06/2006
9	Carrier Proteins (Binding Protein)IBA 12/2020 - 04/2014
9	CaspasesIBA 01/2020 - 12/2006
9	Caspase 1 (ICE Protease)IBA 01/2016 - 12/2008
7	Interferon Type IIBA 01/2021 - 01/2013
7	DNA (Deoxyribonucleic Acid)IBA 01/2020 - 05/2015
6	LigandsIBA 01/2022 - 01/2012
6	Antiviral Agents (Antivirals)IBA 01/2021 - 09/2013
5	InterferonsIBA 02/2022 - 01/2016
5	ChemokinesIBA 01/2022 - 11/2011
5	LipopolysaccharidesIBA 12/2021 - 06/2006
5	PyrinIBA 01/2021 - 02/2017
5	Interleukin-6 (Interleukin 6)IBA 01/2018 - 03/2006
5	Interleukin-1 (Interleukin 1)IBA 11/2016 - 11/2012
4	Dextrans (Dextran)FDA Link 02/2022 - 03/2010
4	sodium sulfate (sodium bisulfate)FDA LinkGeneric 02/2022 - 03/2010
4	Caspase 3 (Caspase-3)IBA 11/2021 - 12/2008
4	Pattern Recognition ReceptorsIBA 01/2021 - 06/2006
4	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2021 - 04/2010
4	Z-Form DNA (Z-DNA)IBA 12/2020 - 01/2018
4	Protein Kinases (Protein Kinase)IBA 11/2020 - 05/2013
4	Proline (L-Proline)FDA Link 01/2020 - 12/2014
4	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 01/2020 - 12/2014
4	InterleukinsIBA 11/2018 - 12/2006
3	RNA (Ribonucleic Acid)IBA 11/2022 - 01/2020
3	AzoxymethaneIBA 02/2022 - 10/2010
3	Transcription Factors (Transcription Factor)IBA 02/2022 - 01/2012
3	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2022 - 05/2015
3	Caspase 6IBA 12/2021 - 01/2020
3	Pharmaceutical PreparationsIBA 01/2021 - 01/2018
3	Cysteine Proteases (Cysteine Protease)IBA 01/2020 - 12/2008
3	Interleukin-33IBA 01/2019 - 12/2016
3	UbiquitinIBA 01/2019 - 08/2006
3	Interleukin-17 (Interleukin 17)IBA 01/2018 - 01/2011
3	FlagellinIBA 01/2018 - 11/2006
3	Leucine (L-Leucine)FDA Link 01/2017 - 05/2015
3	Interleukin-10 (Interleukin 10)IBA 09/2015 - 04/2014
3	Caspase 7IBA 01/2010 - 12/2008
2	MannansIBA 12/2021 - 07/2009
2	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2020 - 01/2020
2	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2020 - 01/2018
2	Biological ProductsIBA 01/2020 - 07/2017
2	Interleukin-4 (Interleukin 4)IBA 01/2020 - 02/2015
2	sharpinIBA 01/2019 - 11/2016
2	Nucleic AcidsIBA 01/2018 - 01/2017
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2018 - 01/2014

Therapy/Procedure

10	Therapeutics 01/2022 - 04/2010
3	Immunotherapy 01/2021 - 04/2010